Microbial and Systemic Effects of SNAC-Enabled Oral Semaglutide Administration
February 20, 2026
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Brand Name :
Tenutex
Synonyms :
benzyl benzoate/disulfiram
Class :
Antiparasitic
Brand Name :
Tenutex
Synonyms :
benzyl benzoate/disulfiram
Class :
Antiparasitic
Dosage Forms & Strengths
Lotion
100 gm
For 13 to 18 years old:
Apply the lotion once onto the affected area of body
Refer to adult dosing
Actions and Spectrum
benzyl benzoate is an organic compound used primarily as an acaricide to treat scabies, a contagious skin condition. It works by killing the mites and their eggs, effectively treating the infestation.
disulfiram is used to treat chronic alcoholism. It works by inhibiting the enzyme aldehyde dehydrogenase, which is involved in the metabolism of alcohol.
Frequency not defined
Mental or mood problems
Tiredness
Vomiting
Nausea
Numbness or tingling of the arms or legs
Seizures
Severe allergic reactions
Dark urine
Loss of appetite
Weakness
Yellowing of the eyes or skin
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Individuals who have a known hypersensitivity or allergy to benzyl benzoate/disulfiram or any of its components should not use this medication.
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
benzyl benzoate displays its action by disrupting the mite’s physiology and metabolism. It penetrates the mite’s exoskeleton and interferes with the mite’s nervous system and respiration, ultimately leading to its death.
disulfiram’s mechanism of action is based on its ability to inhibit the enzyme aldehyde dehydrogenase. This enzyme is responsible for metabolizing acetaldehyde, a toxic byproduct of alcohol metabolism, into acetic acid.
Pharmacodynamics
benzyl benzoate works by penetrating the exoskeleton of the mites and disrupting their nervous system and respiration.
disulfiram inhibits the enzyme aldehyde dehydrogenase, which is responsible for metabolizing acetaldehyde, a toxic byproduct of alcohol metabolism. This leads to an accumulation of acetaldehyde in the body when alcohol is consumed.
Pharmacokinetics
Absorption
benzyl benzoate/disulfiram is applied topically to the skin, and it is absorbed through the skin.
Distribution
benzyl benzoate/disulfiram is distributing throughout the body via the bloodstream.
Metabolism
benzyl benzoate/disulfiram is metabolized in the liver.
Elimination and excretion
benzyl benzoate/disulfiram are excreted in the urine.
Administration
benzyl benzoate/disulfiram is a combination drug applied topically onto the body surface and available in form of emulsion/lotion.
Patient information leaflet
Generic Name: benzyl benzoate/disulfiram
Why do we use benzyl benzoate/disulfiram?
Tenutex (benzyl benzoate/disulfiram) disulfiram is a combination drug is used in the treatment of scabies.
It is also used to treat head lice and pubic lice (crabs).
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